Showing information for HMDB0010396 ('LysoPC(20:4(8Z,11Z,14Z,17Z))')

Metabolite information
HMDB ID HMDB0010396
Synonyms
1-(8Z,11Z,14Z,17Z-eicosapentaenoyl)-glycero-3-phosphocholine
1-Eicsoate
1-Eicsoatetraenoyl-glycero-3-phosphocholine
1-Eicsoic acid
LPC(20:4)
LPC(20:4/0:0)
LPC(20:4W3/0:0)
LPC(20:4n3/0:0)
LyPC(20:4)
LyPC(20:4/0:0)
LyPC(20:4W3/0:0)
LyPC(20:4n3/0:0)
LysoPC a C20:4
LysoPC(20:4(8Z,11Z,14Z,17Z))
LysoPC(20:4)
LysoPC(20:4/0:0)
LysoPC(20:4W3/0:0)
LysoPC(20:4n3/0:0)
Lysophosphatidylcholine(20:4)
Lysophosphatidylcholine(20:4/0:0)
Lysophosphatidylcholine(20:4W3/0:0)
Lysophosphatidylcholine(20:4n3/0:0)
Chemical formula C28H50NO7P
IUPAC name
(2-{[(2R)-2-hydroxy-3-[(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyloxy]propyl phosphonato]oxy}ethyl)trimethylazanium
CAS registry number –
Monoisotopic molecular weight 543.332489471

Chemical taxonomy
Super class None
Class None
Sub class None

Biological properties
Pathways (Pathway Details in HMDB)

The paper(s) that report HMDB0010396 as a lung cancer biomarker

The studies that identify HMDB0010396 as a lung cancer-related metabolite

Reference Country Specimen Marker function Participants (Case) Participants (Control)
Cancer type Stage Number Gender (M,F) Age mean (range) (M/F) Smoking status Type Number Gender (M,F) Age mean (range) (M/F) Smoking status
Wan et al., 2021 China Serum diagnosis squamous cell carcinomas+adenocarcinomas I, II 48 21, 27 59.1 (38-75) smoker, non-smoker healthy 30 – – –
Wan et al., 2021 China Serum diagnosis squamous cell carcinomas+adenocarcinomas I, II 48 21, 27 59.1 (38-75) smoker, non-smoker healthy 30 – – –
Reference Chromatography Ion source Positive/Negative mode Mass analyzer Identification level
Wan et al., 2021 LC ESI both Q-TOF –
Wan et al., 2021 LC ESI both Q-TOF –
Reference Data processing software Database search
Wan et al., 2021 Progenesis QI 2.3 HMDB, Metlin
Wan et al., 2021 Progenesis QI 2.3 HMDB, Metlin
Reference Difference method Mean concentration (case) Mean concentration (control) Fold change (case/control) P-value FDR VIP
Wan et al., 2021 PCA, OPLS-DA, Student’s t test – – – <0.05 – >1
Wan et al., 2021 PCA, OPLS-DA, Student’s t test – – – <0.05 – >1
Reference Classification method Cutoff value AUROC 95%CI Sensitivity (%) Specificity (%) Accuracy (%)
Wan et al., 2021 – – – – – –
Wan et al., 2021 – – – – – –