Metabolite page

Showing information for HMDB0013648 ('N-palmitoleoyl ethanolamide')

Metabolite information
HMDB ID	HMDB0013648
Synonyms	(Z)-Hexadec-9-enoyl ethanolamide N-(2-Hydroxyethyl)palmitoleylamide N-(9Z-Hexadecenoyl) ethanolamine N-(9Z-Hexadecenoyl)-ethanolamide N-(9Z-Hexadecenoyl)-ethanolamine POEA Palmitoleoyl-ea Palmitoleoyl-ethanolamide Palmitoleoyl-ethanolamine Polyoxyethyleneamine
Chemical formula	C18H35NO2
IUPAC name	(9Z)-N-(2-hydroxyethyl)hexadec-9-enamide
CAS registry number	94421-67-7
Monoisotopic molecular weight	297.266779369
Chemical taxonomy
Super class	Organic nitrogen compounds
Class	Organonitrogen compounds
Sub class	Amines
Biological properties
Pathways (Pathway Details in HMDB)

The paper(s) that report HMDB0013648 as a lung cancer biomarker

The studies that identify HMDB0013648 as a lung cancer-related metabolite

Reference	Country	Specimen	Marker function	Participants (Case)						Participants (Control)
Reference	Country	Specimen	Marker function	Cancer type	Stage	Number	Gender (M,F)	Age mean (range) (M/F)	Smoking status	Type	Number	Gender (M,F)	Age mean (range) (M/F)	Smoking status
Wen et al. 2013	China	plasma	diagnosis	adenocarcinoma	I	31	15, 16	median: 63 (40-81)	smoker, non-smoker	healthy	28	20, 8	median: 37 (29-50)	smoker, non-smoker

Reference	Chromatography	Ion source	Positive/Negative mode	Mass analyzer	Identification level
Wen et al. 2013	LC	ESI	–	Q-TOF	MS/MS

Reference	Data processing software	Database search
Wen et al. 2013	MassHunter, Mass Profiler Professional software (Agilent)	NIST 08, HMDB, METLIN, LIPID MAPS

Differential analysis
Classification analysis

Reference	Difference method	Mean concentration (case)	Mean concentration (control)	Fold change (case/control)	P-value	FDR	VIP
Wen et al. 2013	Mann–Whitney–Wilcoxon test, OPLS-DA	–	–	19.03	5.14e-09	–	1.03

Reference	Classification method	Cutoff value	AUROC 95%CI	Sensitivity (%)	Specificity (%)	Accuracy (%)
Wen et al. 2013	ROC curve analysis	–	0.93	–	–	–