Showing information for HMDB0002928 ('maltitol')

Metabolite information
HMDB ID HMDB0002928
Synonyms
(2S,3R,4R,5R)-4-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}hexane-1,2,3,5,6-pentol
4-O-a-D-Glucopyranosyl-D-glucitol
4-O-alpha-D-Glucopyranosyl-D-glucitol
4-O-alpha-delta-Glucopyranosyl-delta-glucitol
4-O-α-D-glucopyranosyl-D-glucitol
Amalti syrup
Amalty MR 100
D-4-O-alpha-D-Glucopyranosylglucitol
D-Maltitol
Malbit
Malti MR
Maltisorb
Maltit
a-D-GLC-(1->4)-D-GLC-ol
a-D-GLCP-(1->4)-D-GLC-ol
a-D-Glucosyl-(1->4)-D-glucitol
alpha-D-GLC-(1->4)-D-GLC-ol
alpha-D-GLCP-(1->4)-D-GLC-ol
alpha-D-Glucosyl-(1->4)-D-glucitol
delta-4-O-alpha-delta-Glucopyranosylglucitol
delta-Maltitol
α-D-GLC-(1->4)-D-GLC-ol
α-D-GLCP-(1->4)-D-GLC-ol
α-D-glucosyl-(1->4)-D-glucitol
Chemical formula C12H24O11
IUPAC name
(2S,3R,4R,5R)-4-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}hexane-1,2,3,5,6-pentol
CAS registry number 585-88-6
Monoisotopic molecular weight 344.13186161

Chemical taxonomy
Super class Lipids and lipid-like molecules
Class Fatty Acyls
Sub class Fatty acyl glycosides

Biological properties
Pathways (Pathway Details in HMDB)

The paper(s) that report HMDB0002928 as a lung cancer biomarker

The studies that identify HMDB0002928 as a lung cancer-related metabolite

Reference Country Specimen Marker function Participants (Case) Participants (Control)
Cancer type Stage Number Gender (M,F) Age mean (range) (M/F) Smoking status Type Number Gender (M,F) Age mean (range) (M/F) Smoking status
Wen et al. 2013 China plasma diagnosis adenocarcinoma I 31 15, 16 median: 63 (40-81) smoker, non-smoker healthy 28 20, 8 median: 37 (29-50) smoker, non-smoker
Reference Chromatography Ion source Positive/Negative mode Mass analyzer Identification level
Wen et al. 2013 LC ESI – Q-TOF MS/MS
Reference Data processing software Database search
Wen et al. 2013 MassHunter, Mass Profiler Professional software (Agilent) NIST 08, HMDB, METLIN, LIPID MAPS
Reference Difference method Mean concentration (case) Mean concentration (control) Fold change (case/control) P-value FDR VIP
Wen et al. 2013 Mann–Whitney–Wilcoxon test, OPLS-DA – – 61.82 4.35e-09 – 1.25
Reference Classification method Cutoff value AUROC 95%CI Sensitivity (%) Specificity (%) Accuracy (%)
Wen et al. 2013 ROC curve analysis – 0.93 – – –